Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers. PLoS Genetics, Vol. 17, (3). Lesseur, Corina

Conclusions We identified 6 loci associated with CAD at genome-wide significance. Several CAD loci show substantial pleiotropy, which may help us

Pleiotropi Definition. av T Ekbom · 2005 · Citerat av 23 — characteristics for a well-designed material can be defined in terms of the amount of absorbed hydrogen, the binding energy of the hydrogen and finally the av M Beato · 2000 · Citerat av 821 — became the first molecularly-defined transcription factors for. RNA polymerase II fermenting (SWI/SNF) complex, a set of pleiotropic transactivators that In this present study we have defined the range of proteins that aggregate in yeast cells during normal growth and after exposure to stress conditions including av L Krubitzer · 2007 · Citerat av 217 — control a number of activities in development (pleiotropy; Hall, 1994), (I use the term epigenetic to mean a characteristic or feature resulting dogs appears to be affected by pleiotropy and are both inherited by means elimination of this trait is unlikely due to pleiotropic interactions. The author then discusses the Pleiotropic Paradox and the development of the promotes glutathione synthesis intracellularly through physiological means. [arv], dessa egenskaper kommer alltid att visas tillsammans och kan verkar således vara korrelerade ". Denna definition används fortfarande idag Torp-Pedersen C T and Waldenstrom A. Metabolic control by means of than pleiotropic effects of statins for endothelial function in patients with dysglycaemia. Prognostic significance of faecal eosinophil granule proteins in inflammatory bowel A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Skolastikerna tog senare upp Aristoteles definition och utvecklade den i kristen Senare forskare har reviderat William Sterns metod och definition av ”Pleiotropy across academic subjects at the end of compulsory education” (på engelska).

This may be an important pleiotropic effect whereby rosuvastatin reduces mortality in patients with coronary artery disease. The pleiotropic effect is produced by a gene owing to a cascade (succession) of reactions during some metabolic pathway which is influenced by the original gene product and contributes to different phenotypic effects. The ratio is 2:1 instead of 3:1. 2021-04-08 If playback doesn't begin shortly, try restarting your device. Up Next.

A. And height is also a multi-factorial trait. What this means is that it's determined by multiple factors.

In pleiotropy, a single gene affects many traits. That means the gene product is used in many types of cells in different tissues. Sometimes, the gene product may act as a signaling molecule, affecting the functions of many tissues. The gene, which is responsible for the coat color of mice is pleiotropic.

The phenotype-genotype relationship in these pathologies will be investigated, particularly the phenomena of penetrance, expressivity, pleiotropic effects and genetic anticipation. ribermov.org Se investigará la relación entre el fenotipo y el genotipo en estas patologías, estudiando particularmente los fenómenos de penetrancia, expresividad , efectos p leiotrópicos y anticipación genética.

the phenomenon of one gene being responsible for or affecting more than one phenotypic characteristic.

More example sentences. ‘Many semidwarf mutants have pleiotropic effects on traits other than culm length.’. ‘Many mutants died or showed pleiotropic defects casting doubt on the specificity of their retinal phenotype and were not Definition of pleiotropic in the Definitions.net dictionary. Meaning of pleiotropic. What does pleiotropic mean? Information and translations of pleiotropic in the most comprehensive dictionary definitions resource on the web.

The white gene in Drosophila 13 Mar 2020 The phenomenon of controlling more than one character at the same time is called pleiotropy or pleiotropism. Such genes are called pleiotropic pleiotropy(Noun). The influence of a single gene on multiple phenotypic traits; pleiotropism · pleiotropy(Noun). The existence of drug effects other than the one for the appropriate answer is always 'What do you mean?'. Multiple traits, multiple meanings. Pleiotropy refers to the phenomenon of a single gene affecting Pleiotropy occurs when one gene influences two or more seemingly unrelated phenotypic traits.
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Statins have pleiotropic effects-that is, they are simultaneously capable of producing more than one benefit, and in cardiovascular risk reduction, they accomplish more than simply lowering cholesterol. It would be a mistake to attribute all beneficial outcomes obtained from statins solely to … plei·o·trop·ic. ( plī'ō-trop'ik ), Denoting, or characterized by, pleiotropy.

Davidson, M. H. Clinical Significance of Statin Pleiotropic Effects Hypotheses Versus Evidence.
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2019-07-11

문법적으로, 이 워드 "pleiotropy" 는 명사, 좀 더 구체적으로, 셀 수 있는 명사 및 단수로만 사용하는 명사. Pleiotropy means that a single gene affects two or more characters.